CURRICULUM VITAE
Name: Yihua Yang, 杨亦桦
Gender: Female
Date of Birth: May 8, 1969
Business Address: College of Plant Protection, Nanjing Agricultural University,
1 Weigang, Xuanwu District, Nanjing 210095, Jiangsu, China
Work Phone: +86-25-84396062
Mobile Phone: +86-13770756390
E-mail: yhyang@njau.edu.cn
Education:
Sep, 2002—Jun, 2005 Nanjing Agricultural University, China
PhD. of Entomology
Dissertation Topic: Biochemical and Molecular Mechanisms of Oxidative Metabolism for Pyrethroid Resistance in Helicoverpa arimgera Hübner
Sep, 1991—Jun, 1994 Nanjing Agricultural University, China
Master degree of Entomology
Thesis Topic: Deltamethrin Resistance in Cotton Bollworm, Helicoverpa armigera Hübner
Sep, 1987—Jun, 1991 Nanjing Agricultural University, China
Bachelor degree of Agricultural Entomology
Sep, 1981—Jun, 1987 Yibin No.1 High School
Work Experience:
Jan, 2010-Present Professor in Entomology, Nanjing Agricultural University
Research on resistance mechanisms to insecticides and transgenic BT cotton and teaching
Feb, 2011-Jul, 2011 Visiting Scientist, Rothamsted Research, UK
Research on the resistance mechanisms to chlorpyrifos of tomato red spider mite, Tetranychus evansi
Aug, 2004-Dec, 2009 Associate Professor in Entomology, Nanjing Agricultural University
Research on resistance mechanisms to insecticides and
transgenic BT cotton and teaching
Dec, 2002-Nov, 2003 Visiting Scientist, Rothamsted Research, UK
Research on the resistance mechanisms to pyrethroid of Helicoverpa armigera
Dec, 2000-May, 2001 Visiting Scientist, Rothamsted Research, UK
Research on the resistance mechanisms to pyrethroid of Helicoverpa armigera
Dec, 1996-Jun, 2004 Lecturer, Nanjing Agricultural University,
Aug, 1994-Dec, 1996 Assistant Professor, Nanjing Agricultural University,
Awards and Group Memberships
2010: Second Prize of National Science and Technology Progress Award, Research and Application of Resistance Risk Assessment and Preventive Management of Cotton Bollworm, Helicoverpa armigera, to Transgenic Bt cotton, Rank Sixth.
2007: Second Prize of Natural Science Award of the Ministry of Education, Biochemical and Molecular Mechanisms of Resistance in Five Important Pest Insects, Rank Sixth.
The member of Entomological Society of China.
Selected Publications:
Haonan Zhang, Shan Yu, Yu Shi, Yihua Yang, Jeff A. Fabrick and Yidong Wu*. 2017. Intra- and extracellular domains of the Helicoverpa armigera cadherin mediate Cry1Ac cytotoxicity. Insect Biochemistry and Molecular Biology 86:41-49.
Jing Wang, Huidong Wang, Shaoyan Liu, Laipan Liu, Wei Tek Tay, Thomas Walsh, Yihua Yang, and Yidong Wu*. 2017. CRISPR/Cas9 mediated genome editing of Helicoverpa armigera with mutations of an ABC transporter gene HaABCA2 confers resistance to Bacillus thuringiensis Cry2A toxins. Insect Biochemistry and Molecular Biology 87:147-153.
Yiyun Wei, Suwen Wu, Yihua Yang and Yidong Wu*. 2017. Baseline susceptibility of field populations of Helicoverpa armigera to Bacillus thuringiensis Vip3Aa toxin and lack of cross-resistance between Vip3Aa and Cry toxins. Toxins 9:127.
Laipan Liu, Meijing Gao, Song Yang, Shaoyan Liu, Yidong Wu, Yves Carrière and YihuaYang*. 2017. Resistance to Bacillus thuringiensis toxin Cry2Ab and survival on single-toxin and pyramided cotton in cotton bollworm from China. Evolutionary Applications 10: 170-179.
Yayun Zuo, Hui Wang, Yanjun Xu, Jianlei Huang, Suwen Wu, Yidong Wu and Yihua Yang*. 2017. CRISPR/Cas9 mediated G4946E substitution in the ryanodine receptor of Spodoptera exigua confers high levels of resistance to diamide insecticides. Insect Biochemistry and Molecular Biology 89:79-85.
Yayun Zuo, Jianlei Huang, Jing Wang,Yue Feng, Tiantian Han, Yidong Wu and Yihua Yang*. 2017. Knockout of a P-glycoprotein gene increases susceptibility to abamectin and emamectin benzoate in Spodoptera exigua. Insect Molecular Biology(DOI: 10.1111/imb.12338).
Jing Wang, Haonan Zhang, Huidong Wang, Shan Zhao, Yayun Zuo, Yihua Yang and Yidong Wu*. 2016. Functional validation of cadherin as a receptor of Bt toxin Cry1Ac in Helicoverpa armigera utilizing the CRISPR/Cas9 system. Insect Biochemistry and Molecular Biology 76: 11-17.
Xingliang Wang, Wen Su, Jianheng Zhang, Yihua Yang, Ke Dong, and Yidong Wu*. 2016. Two novel sodium channel mutations associated with resistance to indoxacarb and metaflumizone in the diamondback moth, Plutella xylostella. Insect Science 23(1): 50-58.
Xingliang Wang, Ran Wang, Yihua Yang, Shuwen Wu, A. O. O'Reilly, and Yidong Wu*. 2016. A point mutation in the glutamate-gated chloride channel of Plutella xylostella is associated with resistance to abamectin. Insect Molecular Biology 25(2): 116-125
Wunan Che, Jianlei Huang, Guan Fang, Yidong Wu, Yihua Yang*. 2015. Cross-resistance and Inheritance of Resistance to Emamectin Benzoate in Spodoptera exigua (Lepidoptera: Noctuidae). Journal of Economic Entomology 108(4): 2015-2020.
Yangchu Han, Wanting Yu, Weiqing Zhang, Yihua Yang, Thomas Walsh, John G. Oakeshott, and Yidong Wu*. 2015. Variation in P450-mediated fenvalerate resistance levels is not correlated with CYP337B3 genotype in Chinese populations of Helicoverpa armigera. Pesticide Biochemistry and Physiology 121: 129-135.
Haonan Zhang，Bing Du，Yihua Yang*，Dawn M Higginson，Yves Carriere，Yidong Wu. 2014. Cadherin mutation linked to resistance to Cry1Ac affects male paternity and sperm competition in Helicoverpa armigera. Journal of Insect Physiology 70:67-72
Wunan Che，Tian Shi，Yidong Wu，Yihua Yang*. 2013. Insecticide Resistance Status of Field Populations of Spodoptera exigua (Lepidoptera: Noctuidae) From China. Journal of Economic Entomology 106(4): 1855-1862.
Yihua Yang, Li Yapeng, Wu Yidong. 2013. Current status of insecticide resistance in Helicoverpa armigera after 15 years of Bt cotton planting in China. Journal of Economic Entomology 106(1):375-381.
Renato Carvalho, Yihua Yang*, Linda M. Field, Kevin Gorman, Graham Moores, Martin S. Williamson, and Chris Bass*. 2012. Chlorpyrifos resistance is associated with mutation and amplification of the acetylcholinesterase-1gene in the tomato red spider mite, Tetranychus evansi.. Pesticide Biochemistry and Physiology 104(2):143-149.
Haonan Zhang, Wen Tian, Jing Zhao, Lin Jin, Jun Yang, Chunhui Liu, Yihua Yang, Shuwen Wu, Kongming Wu, Jinjie Cui, Bruce E. Tabashnik, and Yidong Wu*. 2012. Diverse genetic basis of field-evolved resistance to Bt cotton in cotton bollworm from China. PNAS 109（260）:10275-10280.
Xingliang Wang, Shuwen Wu, Yihua Yang, Yidong Wu*. 2012.Molecular cloning, characterization and mRNA expression of a ryanodine receptor gene from diamondback moth, Plutella xylostella. Pesticide Biochemistry and Physiology 102(3):204-212.
Haonan Zhang, Wei Yin, Jing Zhao, Lin Jin, Yihua Yang, Shuwen Wu, Bruce E. Tabashnik, Yidong Wu*. 2011. Early Warning of Cotton Bollworm Resistance Associated with Intensive Planting of Bt Cotton in China. PLoS ONE 6(8): e22874. doi:10.1371/journal.pone.0022874
Shuwen Wu, Yihua Yang, Guorui Yuan, Peter M. Campbell, Mark G. Teese, Robyn J. Russell, John G. Oakeshott and Yidong Wu*. 2011. Overexpressed esterases in a fenvalerate resistant strain of the cotton bollworm, Helicoverpa armigera. Insect Biochemistry and Molecular Biology 41(1):14-21.
Zhenyu Wang, Haifei Yan, Yihua Yang and Yidong Wu*. 2010. Biotype and insecticide resistance status of the whitefly Bemisia tabaci from China. Pest Management Science 66(12):1360-1366.
Youjing Gong, Chongli Wang, Yihua Yang, Shuwen Wu, Yidong Wu*. 2010. Characterization of resistance to Bacillus thuringiensis toxin Cry1Ac in Plutella xylostella from China. Journal of Invertebrate Pathology 104(2):90-96.
Jing Zhao, Lin Jin, Yihua Yang, Yidong Wu*. 2010. Diverse cadherin mutations conferring resistance to Bacillus thuringiensis toxin Cry1Ac in Helicoverpa armigera. Insect Biochemistry and Molecular Biology 40(2):113-118.
Yihua Yang, Yajun Yang, Weiyue Gao, Jingjie Guo,Yanhong Wu,Yidong Wu*. 2009. Introgression of a disrupted cadherin gene enables susceptible Helicoverpa armigera to obtain resistance to Bacillus thuringiensis toxin Cry1Ac. Bulletin of Entomological Research 99(2):175-181.
Yihua Yang, Lina Yue,Song Chen,Yidong Wu*. 2008. Functional expression of Helicoverpa armigera CYP9A12 and CYP9A14 in Saccharomyces cerevisiae. Pesticide Biochemistry and Physiology 92(2):101-105.
Yajun Yang, Haiyan Chen, Yidong Wu, Yihua Yang, and Shuwen Wu*. 2007. Mutated cadherin alleles from a field population of Helicoverpa armigera confer resistance to Bacillus thuringiensis toxin Cry1Ac. Applied and Environmental Microbiology 71(21):6939-6944.
Yajun Yang, Haiyan Chen, Shuwen Wu, Yihua Yang, Xinjun Xu, Yidong Wu*. 2006. Identification and molecular detection of a deletion mutation responsible for a truncated cadherin of Helicoverpa armigera. Insect Biochemistry and Molecular Biology 36(9):735-740.
Ageng Li, Yihua Yang, Shuwen Wu, Chao Li, Yidong Wu*. 2006. Investigation of resistance mechanisms to fipronil in the diamondback moth (Lepidoptera: Yponomeutidae). Journal of Economic Entomology 99(3):914-919.
Song Chen, Yihua Yang, Yidong Wu*. 2005. Correlation between fenvalerate resistance and cytochrome P450 mediated O-demethylation activity in Helicoverpa armigera (Lepidoptera: Noctuidae). Journal of Economic Entomology 98(3):943-946.
Yang Yihua, Wu Yidong*, Chen Song, Devine Greg J., Denholm Ian, Jewess Pilip, Moores Graham. 2004. The involvement of microsomal oxidases in pyrethroid resistance in Helicoverpa armigera from Asia. Insect Biochemistry and Molecular Biology 34(8):763-773.
Yang Yihua, Zhang Shuang, Zhou Yijun, Yue Lina, Wu Yidong*. 2009. Constitutive overexpression of CYP9A17v2 is involved in pyrethroid resistance in Helicoverpa armigera (Lepidoptera: Noctuidae). Acta Entomologica Sinica 52(8):852-859.
Xu Yonggui, Yang Yihua, Wu Yidong*. 2009. Ligand blot analysis of Bt Cry1A toxin binding with the midgut brush border membrane vesicle receptors of Chilo suppressalis (Lepidoptera: Pyralidae). Acta Entomologica Sinica 52(2):153-158.
Zheng Yangping, Yang Yihua, Wu Yidong*.2008. Metabolic Resistance Meshanisms in a Phoxim -resistant Strain of Helicoverpa armigera. Chinese Journal of Pesticide Science 10(4):410-416.
Yang Yihua, Chen Song, Wu Yidong*. 2008. Cross resistance patterns and biochemical mechanisms in a Chinese Helicoverpa armigera strain selected with an organophosphate/pyrethroid mixture. Cotton Science 20(4):249-255.
Chen Haiyan, Yang Yihua, Wu Shuwen, Yang Yajun, Wu Yidong*. 2007. Estimated frequency of resistance alleles to Bt toxin Cry1Ac in the field populations of Helicoverpa armigera (Hübner) from Northern China. Acta Entomologica Sinica 50(1):25-30.
Yang Yihua, Zheng Yangping, Lin Yan, Wu Yidong* 2007. Inheritance mode of Phoxim resistance of Helicoverpa armigera (Hübner). Journal of Nanjing Agricultural University 30(2):65-67.
(* indicates the corresponding author or the co-first author.)
Travel History in the Past Five Years
Unite Kingdom (2011), South Korea (2012), Unite State of America (2012, 2013,2016), Singapore (2014), Malaysia (2014)
