[Shengkun Li]
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Tel：+86-13675143844 Email：SKL505@outlook.com Research Interest: Novel Chiral Agrochemicals Oriented Synthetic Chemistry and Chemicobiology |
Education Background
2010/10—2013/12 Joint PhD in Chemicobiology and synthetic organic chemistry
Northwest A&F University (China) and Rutgers University (USA)
2007/09—2010/06 M.S. in Applied Chemistry (Ranked 1st)
Northwest A&F University
2003/09—2007/06 B.S.in Pharmaceutical Engineering (Ranked 1st)
Northwest A&F University
Work Experience
2014/01— Associate Professor, Nanjing Agricultural University
Research Interest
Novel Chiral Agrochemicals Oriented Synthetic Chemistry and Chemicobiology (Peptidomimetics and Drimane Natural Products).
Mainly Funded by national natural science foundation of china, natural science foundation of Jiangsu Province and Nanjing Agricultural University, etc.
Representative Publications
(ORCID:https://orcid.org/0000-0001-5458-0811; ResearcherID: K-9108-2017)
(1) Dangdang Li, Shasha Zhang, Zehua Song, Wei Li, Feng Zhu, Jiwen Zhang and Shengkun Li*, Synthesis and bio-inspired optimization of drimenal: Discovery of chiral drimane fused oxazinones as promising antifungal and antibacterial candidates, Eur. J. Med. Chem., 2018, 143,558-567
(2) Shasha Zhang, Dangdang Li, Zehua Song, Chuanli Zang, Lu Zhang, Xiushi Song, and Shengkun Li*, “Carbon Assimilation” Inspired Design and Divergent Synthesis of Drimane Meroterpenoid Mimics as Novel Fungicidal Leads. J. Agric. Food Chem. 2017, 65(41), 9013-9021.
(3) Dangdang Li, Shasha Zhang, Zehua Song, Guotong Wang, Shengkun Li*, Bioactivity- guided mixed synthesis accelerate the serendipity in lead optimization: Discovery of fungicidal homodrimanyl amides. Eur. J. Med. Chem. 2017, 136, 114-121.
(4) Shengkun Li*, Dangdang Li, Taifeng Xiao, ShaSha Zhang, Zehua Song, and Hongyu Ma，Design, Synthesis, Fungicidal Activity, and Unexpected Docking Model of the First Chiral Boscalid Analogues Containing Oxazolines，J. Agric. Food Chem. 2016, 64, 8927−8934。
(This work was highlighted by JAFC editors).
(5) Shengkun Li*, Taifeng Xiao, Dangdang Li, and Xumu Zhang*，First Iridium-Catalyzed Highly Enantioselective Hydrogenation of β-Nitroacrylates. Org. Lett.; 2015, 17, 3782−3785.
(This work was highlighted by X-MOL)
(6) Shengkun Li*, Kexuan Huang, and Xumu Zhang*, Highly Enantioselective Hydrogenation of α, β-nitroalkenes. Chem. Commun., 2014, 8878-8881. (This work was highlighted by Synfacts, Synfacts 2014, 10(10), 1058)
(7) Shengkun Li, Kexuan Huang, Jiwen Zhang, Wenjun Wu*, and Xumu Zhang*， Cascade Synthesis of Fenpiprane and Related Pharmaceuticals via Rhodium-Catalyzed Hydroaminomethylation, Org. Lett.; 2013, 15 (5), 1036–1039.
(This work was highlighted by Synfacts, Synfacts 2013, 9(6), 0578)
(8) Shengkun Li, Kexuan Huang, Jiwen Zhang, Wenjun Wu*, and Xumu Zhang*，Rhodium-Catalyzed Highly RegioselectiveHydroaminomethylation of Styrenes with Tetraphosphorus Ligands, Org. Lett.; 2013, 15 (12), 3078–3081.
(9) Shengkun Li, Kexuan Huang, Jiwen Zhang, Wenjun Wu*, and Xumu Zhang*，Rh-Catalyzed Highly Enantioselective Hydrogenation of Nitroalkenes under Basic Conditions. Chem. Eur. J. ; 2013,19(33),10840-10844.
(10) Shengkun Li, Kexuan Huang, Bonan Cao, Jiwen Zhang, Wenjun Wu*, and Xumu Zhang*，Highly Enantioselective Hydrogenation of β,β-Disubstituted Nitroalkenes . Angew. Chem. Int. Ed. 2012, 51(34), 8573-8576.
(This work was highlighted by Synfacts, Synfacts 2012, 8(11), 1232 )
(11) Shengkun Li, Zhiqin Ji，Jiwen Zhang，Zhengyan Guo，Wenjun Wu，Synthesis of 1-Acyl-3-isopropenyl- benzimidazolone Derivatives and Their Activity against Botrytis cinerea. J. Agric. Food Chem., 2010, 58, 2668-2672.
(12) Shengkun Li, Bing Yang，Qianling Zhang，Jiwen Zhang，Junru Wang，Wenjun Wu. Synthesis and Bioactivity of β-Carboline Derivatives. Nat. Prod. Commun. 2010, 5, 1591-1596.
Selected Awards
Hongkong Scholarship, ACS Membership Award, Zhongshan Award
